Suchergebnisse
Suchergebnisse:
7. März 2018 · Synovial sarcoma (SS) is a rare, yet highly malignant, type of soft tissue sarcoma (STS), for which survival has not improved significantly during the past years. In this review, we focus on systemic treatment in adults. Compared to other STS, SS are relatively chemosensitive. Ifosfamide and ifosfamide combinations are active in different lines ...
11. März 2024 · Symptoms of synovial sarcoma are often not noticeable early on. These tumors are typically slow growing, and symptoms can go unnoticed for years before a diagnosis is made. As the tumor grows, the first thing a person might notice is swelling or a lump in the area of the cancer. If the tumor is pressing on a nerve, pain can be the first sign of ...
29. Feb. 2024 · Synovial sarcoma is a misnomer because this tumor shows no synovial differentiation but reveals somehow epithelial differentiation, so it stains for epithelial markers (e.g. epithelial membrane antigen and cytokeratin), which synovium does not. Additionally, it has been found in many locations that do not normally have synovium.
After imaging studies, the next step in diagnosis is a biopsy to remove a sample of the tumor for further analysis. Among the different types of biopsies, open biopsy (a surgical incision is made to remove the sample) or core needle biopsy (a large needle is used to take the sample) are preferred. The use of a fine needle to remove cells can ...
14. Juni 2024 · Summary. Synovial Sarcoma is a malignant, soft tissue sarcoma caused by a t (X;18) chromosomal translocation mutation ( SS18:SSX fusion protein) most commonly found near joints but rarely within the joint. The condition usually presents in patients between 15 and 40 years old with a growing mass in proximity to a joint. Diagnosis is made with a ...
S3-Leitlinie Adulte Weichgewebesarkome. LL_Weichgewebesarkome_Langversion_1.1.pdf 5 MB. LL_Weichgewebesarkome_Kurzversion_1.1.pdf 3 MB. LL_Weichgewebesarkome_Leitlinienreport_1.1.pdf 2 MB. Evidenzbericht_LL_Adulte_Weichgewebesarkome.pdf 2 MB. LL_Adulte_Weichgewebesarkome_Evidenztabellen_1.0.pdf 3 MB.
These tumors are rare. With an annual incidence of around 2-3/100,000, they account for less than 1% of all malignant tumors and 2% of all cancer-related deaths, although in children soft tissue sarcomas represent about 8% of all malignancies. Synovial sarcoma (SS) represents one of the most frequent malignant tumors of soft tissues, accounting ...
