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20. Nov. 2020 · Intermittent ROSC before ED arrival: 33.3% v 26.6%. Time from 911 call to EMS arrival: 6 v 7 min. Time from cardiac arrest to 1st shock: 8.5 v 7 min. EMS scene time: 22.5 v 23 min. Transport time: 19 v 20 min. Time to randomisation: 48.5 minutes v 51.8 minutes. Arriving with ROSC at ED: 0 v 0.
Home. A randomised trial of expedited transfer to a cardiac arrest centre for non-ST elevation out-of-hospital cardiac arrest (ARREST) Randomised controlled interventional trial. Aim: The aim is to determine the best post-resuscitation care pathway for patients without ST-segment elevation (STE). Primary endpoint: All-cause mortality at 30 days.
29. Feb. 2024 · The ARREST Trial took 11 months to enroll 30 participants. In the Prague trial, 4345 patients were assessed for eligibility over 91 months to enroll 264 participants out of 358 patients with refractory arrest. The INCEPTION trial lasted 45 months with a brief pause during the pandemic to enroll 134 participants. Thus, trial enrollment in both ...
27. Aug. 2023 · The ARREST trial investigated whether expedited transfer of OHCA patients to a cardiac arrest centre reduces mortality compared with delivery to the closest emergency department. The trial also examined whether there was any difference in neurological outcomes with the two strategies. This was a randomised controlled trial conducted pre-hospital across the whole of London examining a pathway ...
17. Feb. 2018 · Methods: In this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years) with S aureus bacteraemia who had received ≤96 h of active antibiotic therapy were recruited from 29 UK hospitals. Patients were randomly assigned (1:1) via a computer-generated sequential randomisation list to receive 2 weeks of adjunctive rifampicin (600 mg or 900 mg per day according to ...
13. Nov. 2020 · This trial was terminated due to the finding of survival benefit from ECMO. Early ECMO achieves three goals: 1) normalizes perfusion; 2) allows time to identify and treat severe coronary artery disease, which is the most common cause of cardiac arrest; and 3) provides a bridge to recovery in the intensive care unit during predictable subsequent multi-organ failure.
14. Dez. 2020 · Yannopoulos D, Bartos J, Raveendran G, Walser E, et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. Lancet. 2020 Nov 12:S0140-6736 (20)32338-2. doi: 10.1016/S0140-6736 (20)32338-2.