Suchergebnisse
Suchergebnisse:
18. Mai 2020 · Deeper divergences pose a greater challenge to the inference of a gene tree as the phylogenetic signal erodes (that is, multiple mutations accumulate resulting in homoplasy) and the risk of...
- Paschalia Kapli, Ziheng Yang, Maximilian J Telford
- 2020
25. Aug. 2021 · Nature - Somatic mutations obtained from laser microdissected biopsies of human tissues are used to reconstruct the developmental phylogenies of these tissues back to the zygote.
- Tim H. H. Coorens, Luiza Moore, Luiza Moore, Philip S. Robinson, Philip S. Robinson, Rashesh Sanghvi...
- 2021
23. Feb. 2024 · The resulting phylogenies can then serve as a basis for many subsequent analyses, including investigating embryonic development, tissue dynamics in health and disease, and mutational signatures...
29. Apr. 2022 · Phylogenies should not be read as accurate records of history, but as a way of exploring plausible explanations for current patterns of diversity. Phylogenies provide important information that can be used to test ideas about human diversity, and can help to guard against errors of inference arising from statistical artifacts.
24. Feb. 2023 · Information about genes, proteins, and genomes that is acquired from several ‘omics technologies is further gathered in the Kyoto Encyclopedia of Genes and Genomes (KEGG) . The KEGG database focuses on metabolism, biological pathways, and human diseases. Summaries of the entire human proteome using antibody-based proteomics ...
5. Okt. 2015 · Morphology remains a powerful independent source of evidence for testing molecular clades, and — through fossil phenotypes — the primary means for time-scaling phylogenies. Morphological phylogenetics is therefore vital for transforming undated molecular topologies into dated evolutionary trees. However, if morphology is to be ...
disabling mutations, segmental duplications, and gene- enabling mutations. The new genetic tools also provide fascinating insights into when, and how, many features of human biology arose: from aspects of placental structure; vitamin C- dependence and trichromatic vision; to tendencies to gout, cardiovascular disease and cancer.
