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Suchergebnisse

  1. Suchergebnisse:
  1. 16. Jan. 2018 · He challenged his head chemist, Harold Watkins, to make a sweet, liquid form of sulfanilamide. After much experimentation, Watkins found that a solvent, diethylene glycol, could dissolve...

  2. www.fda.gov › about-fda › histories-product-regulationSulfanilamide Disaster | FDA

    The company's chief chemist and pharmacist, Harold Cole Watkins, experimented and found that sulfanilamide would dissolve in diethylene glycol. The company control lab tested the mixture for...

  3. DEG is poisonous to humans and other mammals, but Harold Watkins, the company's chief pharmacist and chemist, was not aware of this. (Although the first case of a fatality from the related ethylene glycol occurred in 1930 and studies had been published in medical journals stating DEG could cause kidney damage or failure, its toxicity ...

  4. 12. Nov. 2023 · Die gesamte Gruppe der Sulfonamide ist bekannt für ihre schlechte Löslichkeit und einen bitteren Geschmack. Harold Watkins, der Chemiker in der neu gegründeten Firma, suchte daher nach einem geeigneten Lösungsmittel für Sulfanilamid und kam zu folgender Rezeptur: 10 Prozent Sulfanilamid, 72 Prozent Diethylenglykol, 16 Prozent Wasser

    • Ulrike Holzgrabe
  5. 20. Apr. 2010 · Company chemist Harold Watkins dissolved the drug in a 10% solution of diethylene glycol mixed with raspberry flavoring and sweetened with saccharin. Over the next two months 105 people died from liver and kidney damage caused by the solvent. Watkins killed himself after he learned of the lethal effects of the “Elixir.” All the ...

  6. A coroner’s verdict was reserved today in the death of Harold Cole Watkins, chemist who prepared the formula for elixir of sulfanilamide which was blamed for the deaths of 67 persons in 1937. Watkins, 58, was found dead of a bullet wound through the heart at his home. .

  7. 1. Okt. 2022 · His chief chemist did not agree. Horrified at the deaths his recipe had caused, on Jan. 17, 1939, Harold Watkins died by suicide, using a gun to shoot himself in the heart.