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A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes unconsciousness.
- Local anesthesia
A local anesthetic is a drug that causes reversible local...
- Anesthetic
Local anesthetics can be either ester- or amide-based. Ester...
- Local anesthesia
General anaesthetics are a structurally diverse group of compounds whose mechanisms encompass multiple biological targets involved in the control of neuronal pathways. The precise workings are the subject of some debate and ongoing research. [1] General anesthetics elicit a state of general anesthesia.
15. März 2022 · Local anesthetics are the defining medication class for regional and local anesthesia. They transiently inhibit sensory, motor, and autonomic nerve function depending on location/route of administration and dosage. Contents. 1 Uses. 2 Contraindications. 2.1 Absolute contraindications. 2.2 Precautions. 3 Pharmacology. 3.1 Pharmacodynamics.
4. Dez. 2019 · Key points. •. Local anaesthetic agents are amphipathic molecules. •. They bind primarily to sodium channels but also to potassium and calcium channels, and G-protein-coupled receptors. •. Structural modifications alter the physicochemical characteristics of a local anaesthetic. •.
Jerome M. Adams MD, MPH & Jesse M. Ehrenfeld MD, MPH. 4780 Accesses. Abstract. Understand the basic mechanisms of local anesthetic action and metabolism. For maximum impact, it is recommended that the case study and questions found on page xix are reviewed before reading this chapter. Download chapter PDF. Similar content being viewed by others.
