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   mate1是什么

   mate1 interaction

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   mate1 interaction with humans

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1. en.wikipedia.org › wiki › Multidrug_and_toxin_extrusion_protein_1Multidrug and toxin extrusion protein 1 - Wikipedia

   en.wikipedia.org › wiki › Multidrug_and_toxin_extrusion_protein_1

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   Multidrug and toxin extrusion protein 1 (MATE1), also known as solute carrier family 47 member 1, is a protein that in humans is encoded by the SLC47A1 gene. SLC47A1 belongs to the MATE (multidrug and toxic compound extrusion) family of transporters that are found in bacteria, archaea and eukaryotes.

2. www.solvobiotech.com › transporters › mate1MATE1 - Transporters - Solvo Biotechnology

   www.solvobiotech.com › transporters › mate1

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   MATE1 is a poly-specific transporter that mediates the efflux of organic cations, such as metformin, in the kidney and the liver. Learn about its function, localization, substrates, inhibitors, polymorphisms, and clinical relevance.

3. Videos

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     Mate1: The Good, The Bad and The Ugly

     18. Aug. 2014

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     bilibili.com

     华为Mate系列的开山鼻祖，Mate1代上手体验

     2. Aug. 2020

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   • 4:47

     bilibili.com

     使用华为mate1看「我的梦」

     25. Sept. 2023

     4.7K Aufrufe

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4. pubmed.ncbi.nlm.nih.gov › 22149660Interaction of human multidrug and toxin extrusion 1 (MATE1 ... -...

   pubmed.ncbi.nlm.nih.gov › 22149660

   MATE1 is highly expressed in the kidney, liver, skeletal muscle and also in adrenal glands, testes and heart. MATE1 exchanges organic cations against protons both in influx as well as in efflux modes. Methods: Here, we examined the interaction of 25 antineoplastic agents with human MATE1.

   • Autor: Julia Grottker, Albert Rosenberger, Gerhard Burckhardt, Yohannes Hagos

   • Publish Year: 2011

5. www.deutsche-apotheker-zeitung.de › pharmazie › arzneimittelEvrysdi®: Risdiplam - DAZ.online

   www.deutsche-apotheker-zeitung.de › pharmazie › arzneimittel

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   1. Mai 2021 · In vitro zeigte sich Risdiplam als Inhibitor der Effluxtransporter MATE1 oder MATE2-K (Multidrug and Toxin Extrusion Protein 1 und 2-K). Bis zur Klärung der klinischen Relevanz dieses Befundes ...

6. www.nature.com › articles › bcj201679MATE1 regulates cellular uptake and sensitivity to imatinib in...

   www.nature.com › articles › bcj201679

   16. Sept. 2016 · Here we found that the multidrug and toxin extrusion protein 1 (MATE1) transports imatinib with a manifold higher affinity. MATE1 mainly mediates the cellular uptake of imatinib into targeted...

   • Autor: S Harrach, C Schmidt-Lauber, T Pap, H Pavenstädt, E Schlatter, E Schmidt, W E Berdel, U Schulze, B E...

   • Publish Year: 2016

7. journals.physiology.org › doi › fullWide variety of locations for rodent MATE1, a transporter protein...

   journals.physiology.org › doi › full

   1. Okt. 2006 · Human MATE1 (hMATE1) is predominantly expressed and localized to the luminal membr... Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations | American Journal of Physiology-Cell Physiology

8. www.nature.com › articles › jhg20081Identification of multidrug and toxin extrusion (MATE1 and ... -...

   www.nature.com › articles › jhg20081

   9. Jan. 2009 · H+/organic cation antiporters (multidrug and toxin extrusion: MATE1 and MATE2-K) play important roles in the renal tubular secretion of cationic drugs. We have recently identified a regulatory ...