Yahoo Suche Web Suche

Anmelden

Suchergebnisse

  1. Suchergebnisse:

  1. www.nature.com › articles › nj7569-415aTurning point: Martin Jinek | Nature

    16. Sept. 2015 · Structural biologist Martin Jinek helped to launch the genome-modification craze that is upending biological research. Now running his own laboratory at the University of Zurich in Switzerland ...

  2. www.uitzendinggemist.net › programmas › 18188-JinekJinek gemist? Bekijk hier alle uitzendingen terug. Jinek ...

    Eva Jinek voert het gesprek van de dag met de hoofdrolspelers uit de actualiteit: journalistieke, scherpe en onderhoudende gesprekken over media, cultuur, sport en maatschappij. ... 09-09-2019. KRO-NCRV. Alle afleveringen bekijken.

  3. www.youtube.com › watchGenieten! Eva Jinek op haar best - DE VIJF - YouTube

    7. Jan. 2018 · Haar heerlijkste momenten, een jubileum en binnenkort een nieuwe prijs? In De Vijf de hoogtepunten van tien jaar Eva Jinek.

  4. www.nature.com › articles › s41586/022/05114-0R-loop formation and conformational activation mechanisms of Cas9

    24. Aug. 2022 · Formation of a complete R-loop leads to the activation of the Cas9 HNH and RuvC nuclease domains to catalyse cleavage of the TS and non-target DNA strand (NTS), respectively 2, 8, 13. Although ...

  5. pubmed.ncbi.nlm.nih.gov › 22745249A programmable dual-RNA-guided DNA endonuclease in adaptive ... -...

    17. Aug. 2012 · The dual-tracrRNA:crRNA, when engineered as a single RNA chimera, also directs sequence-specific Cas9 dsDNA cleavage. Our study reveals a family of endonucleases that use dual-RNAs for site-specific DNA cleavage and highlights the potential to exploit the system for RNA-programmable genome editing.

  6. www.sohu.com › a › 423839646_682259消失在诺奖光环里的人：这8位为CRISPR做出重要贡献的研究生和博士后，...

    10. Okt. 2020 · 他们会提到‘2012年 Martin Jinek那篇文章’，但是几乎没有人知道 Martin Jinek是谁。” Martin Jinek是一篇开创性文章的第一作者，这篇文章发现，仅仅在一条短链 RNA 的引导之下，Cas9 酶就可以靶向作用于特定的 DNA 序列。那之后他发现，CRISPR 定义了他的人生。踏入 ...

  7. www.nature.com › articles › nature13579Structural basis of PAM-dependent target DNA recognition by ... -...

    27. Juli 2014 · Martin Jinek and colleagues have solved the structure of Cas9 bound to a guide RNA and a PAM-containing duplex DNA. The structure reveals how base-specific recognition of PAM in the DNA target ...