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Stephen Lippard Connected to: {{::readMoreArticle.title}} aus Wikipedia, der freien Enzyklopädie. Stephen Lippard Stephen James Lippard (* 12. Oktober 1940 in Pittsburgh, Pennsylvania) ist ein US-amerikanischer Chemiker. Leben und Wirken. Lippard erwarb ...
14. Mai 2020 · Dr. Stephen Lippard illustrates what marks exceptional scientists and what drives extraordinary discoveries in science.Dr. Lippard is the Arthur Amos Noyes P...
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Stephen J. Lippard. 2004. National Medal of Science. Chemistry. For pioneering research in bioinorganic chemistry, which enriched our understanding of how metal compounds interact with DNA, provided important synthetic models for the active sites of metalloproteins, and elucidated key structural and mechanistic features of methane monooxygenase.
Professor Lippard’s laboratory discovered and named the first metallointercalators, platinum terpyridine complexes that insert between the DNA base pairs and unwind the duplex. This research was followed by extensive studies of the covalent interactions of cisplatin and related anticancer drugs with DNA. Included are the X-ray structural characterization of the major Pt-DNA adducts, 1,2 ...
Zastrow ML, Huang Z, Lippard SJ. (2020) HaloTag-based hybrid targetable and ratiometric sensors for intracellular zinc. Acs Chemical Biology: Almaqwashi AA, Zhou W, Naufer MN, et al. (2019) DNA intercalation facilitates efficient DNA-targeted covalent binding of phenanthriplatin. Journal of the American Chemical Society: Steinhuebel DP, Lippard SJ.
3. Nov. 2014 · Professor Stephen J. Lippard, the Arthur Amos Noyes Professor of Chemistry, has been selected to receive the 2015 Benjamin Franklin Medal in Chemistry for his pioneering research and wide-ranging contributions to the field of bioinorganic chemistry, including protein structure determination, active site characterization, and mechanistic studies by a wide range of physical methods, and the ...
Stephen J. Lippard In: Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy , Stephen B. Howell, Ed., Plenum Press: New York, 1-12 (1991). X-ray Absorption, Mössbauer, and EPR Studies of the Dinuclear Iron Center in the Hydroxylase Component of Methane Monooxygenase .
