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  1. The mammalian neocortex is a complex, highly organized, six-layered structure that contains hundreds of different neuronal cell types and a diverse range of glia 1,2.It is the region of the brain ...

  2. 1. Dez. 2021 · Neocortex size has increased remarkably since the divergence of the lineage leading to the chimpanzee and bonobo from that leading to humans, notably modern humans, around 7 million years ago. The human cerebral cortex is three times bigger than that of the chimpanzee and is estimated to contain twice the number of neurons [26,27]. The emergence of human-specific genes may have contributed to ...

  3. The size and surface area of the mammalian brain are thought to be critical determinants of intellectual ability. Recent studies show that development of the gyrated human neocortex involves a lineage of neural stem and transit-amplifying cells that forms the outer subventricular zone (OSVZ), a proliferative region outside the ventricular epithelium. We discuss how proliferation of cells ...

  4. 13. Mai 2021 · The neocortex, a six-layer neuronal brain structure that arose during the evolution of, and is unique to, mammals, is the seat of higher order brain functions responsible for human cognitive abilities. Despite its recent evolutionary origin, it shows a striking variability in size and folding complexity even among closely related mammalian ...

  5. 27. Jan. 2015 · The developing neocortex shows graded expression of some transcription factors across its surface, through which neocortical arealization is developmentally orchestrated (for example, refs. 56 ...

  6. 1. Jan. 2019 · Abstract. Human neocortex evolved in a series of ancestors with less neocortex and fewer cortical areas. Thus, early mammals had little neocortex and roughly 20 cortical areas, while early primates had much more cortex and around 50 cortical areas. Humans have the largest of primate brains that is 80% neocortex with about 200 areas.

  7. link.springer.com › referenceworkentry › 10Neocortex | SpringerLink

    1. Jan. 2022 · Definition. The neocortex is a portion of the cerebral cortex found exclusively in mammals. It is a six-layered structure, broken into distinct areas, each with their own laminar appearance, connectivity, and functional properties. Its organization, accessibility, and size (particularly in primates) have made it one of the most studied portions ...

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