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    AnzeigeHigh Throughput Sequencing - Screening Library

    Our compound libraries can classified as Bioactive Libraries, Natural Product Libraries,. Fragment Libraries, and Diversity Sets.High Thoughput Screening.Top Publications Citing.

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  1. genomebiology.biomedcentral.com › articles › 10Measuring the reproducibility and quality of Hi-C data

    19. März 2019 · Background Hi-C is currently the most widely used assay to investigate the 3D organization of the genome and to study its role in gene regulation, DNA replication, and disease. However, Hi-C experiments are costly to perform and involve multiple complex experimental steps; thus, accurate methods for measuring the quality and reproducibility of Hi-C data are essential to determine whether the ...

  2. academic.oup.com › nar › articleIntegration of Hi-C and ChIP-seq data reveals distinct types of...

    6. Juni 2012 · By integrating multiple genome-wide data sets from K562 cells, including Hi-C data, ChIP-seq for 45 transcription factors and 9 histone modifications, DNase hypersensitivity assays and RNA-seq data, we have identified 12 distinct sets of chromatin linkages comprising a total of 96 137 sets of two spatially separated interacting loci, shown that ...

  3. www.nature.com › articles › s41587/021/01034-yMultiscale and integrative single-cell Hi-C analysis with Higashi...

    11. Okt. 2021 · The co-assayed single-cell methylation and Hi-C dataset (sn-m3C-seq) was from ref. 17. We followed the same processing pipeline as sn-m3C-seq for processing the methylation signals.

  4. emea.illumina.com › hi-c-3c-seq-capture-cHi-C/3C-Seq/Capture-C - emea.illumina.com

    Hi-C, 3C-Seq, and Capture-C comprise a family of methods for analyzing chromatin interactions. Capture-C adds an additional pull-down of the biotinylated fragments with magnetic beads to the 3C method. A new refinement of the Capture-C method (NG Capture-C) is available. The Hi-C approach extends 3C-Seq to map chromatin contacts genome-wide ...

  5. www.nature.com › articles › s42003/021/02089-yRegulation of mammalian 3D genome organization and histone H3K9...

    13. Mai 2021 · All reads from the RNA-seq, ChIP-seq, and Hi-C experiments generated in this study have been submitted to Gene Expression Omunibus under accession number GSE169106. Read number of NGS data are ...

  6. www.science.org › doi › 10Linking genome structures to functions by simultaneous...

    8. Juni 2023 · Recently, monomodal single-cell Hi-C and RNA sequencing (RNA-seq) assays were applied to postnatal mouse brains, and cell types identified separately from the two types of data were matched for joint three-dimensional (3D) genome and transcriptome analysis ( 4 ). However, because 3D genome changes may either precede or follow transcriptome ...

  7. www.activemotif.jp › catalog › 1317Hi-C 受託解析サービス - Active Motif

    Hi-Cの概要. 核内のDNAは、クロマチン複合体として効率よく折りたたまれた構造をしています。. この高度に制御された構造により、数千kb離れた距離の遺伝子領域が、共同して遺伝子発現を制御することが知られています。. アクティブ・モティフの提供する ...