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The Lancet. 2008 Oct 18;372 (9647):1411-26. Shen SC, Ham TH, Fleming EM. Studies on the destruction of red blood cells: mechanism and complications of hemoglobinuria in patients with thermal burns: spherocytosis and increased osmotic fragility of red blood cells. New England Journal of Medicine. 1943 Nov 4;229 (19):701-13.
Peripheral blood film from a patient with haemoglobin SC disease. The blood film shows typical features of SC disease, including polychromasia, SC poikilocytes, SC crystals, target cells and occasional sickle cells. There are also features of splenectomy - the patient has Howell-Jolly bodies, occasional acanthocytes and a mild platelet ...
8. Okt. 2020 · Procedure. • Thin blood films (only) – Dip Method. 1. Dip air-dried blood film in the undiluted stain for 15 to 30 seconds (double the staining time for bone marrow smears). 2. Remove the color of the stained smears by immersion in distilled or deionized water and air dry. 3. Let air dry in a vertical position.
8. Sept. 2021 · Plasma cells are specialised immune cells derived from B cells which secrete antibodies. They are not usually seen within the peripheral blood except in severe infection and plasma cell dyscrasias. Morphologically plasma cells are medium-to-large cells with a deep blue cytoplasm and a perinuclear 'hof' (area of pallor adjacent to the nucleus ...
This 'Red Cell Morphology' module takes you through a systematic method of examination of red cell morphology. It starts with a basic approach in '2.1 Red Cell Morphology Basics', then examines red cell quantity and red cell quality in '2.2 Describing Microcytic, Macrocytic and Normocytic Anaemias in blood films' and '2.3 Recognising and describing common poikilocoytes'.
A blood film or peripheral blood smear is a thin layer of blood smeared on a microscope slide and then stained in such a way to allow the various blood cells to be examined microscopically. Blood films are usually examined to investigate disorders of the blood and, occasionally, to look for parasites within the blood such as malaria and filaria ...
The most numerous cells in a blood film are the red cells, also known as erythrocytes. Haematology laboratories perform various measurements relating to the haemoglobin content of the blood, the characteristics of red cells, and the number of red cells, white cells and platelets. The purpose of performing a blood count and examining a blood ...
