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  1. Vor 22 Stunden · Subsequently, we calculated the Pearson’s correlation coefficient (r) of the relative evolutionary rates between a given gene and the mtOXPHOS supergene (13 concatenated mtOXPHOS genes) using a ...

  2. Vor 4 Tagen · Gene therapy is the genetic engineering of humans, generally by replacing defective genes with effective ones. Clinical research using somatic gene therapy has been conducted with several diseases, including X-linked SCID, chronic lymphocytic leukemia (CLL), and Parkinson's disease.

  3. 16. Mai 2024 · The gene coexpression was analyzed with the Pearson test. We defined the coexpression gene partners as the top 30 coexpressed genes with significant interaction signals for each de novo gene (P < 10 −5). We also randomly picked up duplicated genes for comparison (180). The ISD Prediction Based on Sequences

  4. 23. Mai 2024 · Methods: In this study, a novel biomarker recognition method was proposed tailored for cancer stages by considering the change of gene expression relationships. Utilizing the sample-specific information and protein-protein interaction networks, the group specific networks were constructed to address the limited specificity of ...

  5. 27. Mai 2024 · Genetic engineering, the artificial manipulation, modification, and recombination of DNA or other nucleic acid molecules to modify an organism. The term is generally used to refer specifically to methods of recombinant DNA technology. Learn about the history, techniques, and applications of genetic engineering.

  6. 28. Mai 2024 · Besides, we conducted a pairwise gene-gene Pearson correlation analysis using TIMER2 tool to further analyze the relationship between TCF3 and related genes in TCGA tumors. The heat map of the selected gene expression profile includes the partial correlation (cor) and P-value in the purity-adjusted Spearman’s rank correlation test.