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15. Mai 2024 · Earlier this year, Lululemon’s founder Chip Wilson went public with his rare disease diagnosis of facioscapulohumeral muscular dystrophy type 2, or FSHD type 2, in which the muscles degenerate over time. Wilson also committed $100 million to find a cure for FSHD through a new venture, Solve FSHD. Chip Wilson Now, up to $10 million ...
Vor 5 Tagen · Wilson has in recent years spent more than $100 million on research for anti-aging and a cure for his particular form of muscular dystrophy. He lives in Vancouver.
13. Mai 2024 · Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder characterized by progressive and asymmetric weakening of facial, scapular girdle, and upper limb skeletal muscles [1, 2].
- Mingtao Huang
13. Mai 2024 · Dystrophin is a large protein crucial for stabilizing the sarcolemma of muscle fibers. Therefore, the malfunction of dystrophin leads to the progressive damage of muscle fibers, resulting in muscle wasting and weakness as healthy tissue is replaced by inflammatory changes and fibrosis [ 24, 25 ].
14. Mai 2024 · The U.S. Food and Drug Administration (FDA) has granted breakthrough therapy designation to delpacibart etedesiran (del-desiran, previously called AOC 1001), an investigational treatment for myotonic dystrophy type 1 (DM1) that’s about to enter Phase 3 clinical testing.
- Senior Science Writer
1. Juni 2024 · Duchenne muscular dystrophy (DMD) is an X-linked progressive disorder associated with muscle wasting and degeneration. The disease is caused by mutations in the gene that encodes dystrophin, a protein that links the cytoskeleton with cell membrane proteins.
21. Mai 2024 · The authors focus on Duchenne muscular dystrophy. This hereditary pathology, initially caused by the loss of the dystrophin protein (primarily in muscle tissue), is also accompanied by a complex of disorders leading to the rapid progression of the pathology and early death of patients.
