Suchergebnisse
Suchergebnisse:
11. Mai 2024 · Promoter capture Hi-C (PCHi-C) [79] is a specialized Hi-C method designed for identifying interactions involving promoters throughout the genome. It has been used to map cCREs to their target genes in various tissue types and cell lines. Notable examples include studies conducted by Jung
17. Mai 2024 · In this work, we provide a DDPM-based computational method named HiC2MicroC to learn the mapping relationships between Hi-C and Micro-C. The only input of our method is Hi-C contact maps, which play a conditional role in DDPM. We trained our method using the Hi-C and Micro-C data from HFFc6 and evaluated our methods in six different ...
14. Mai 2024 · Advances in single-cell technologies, such as single-cell RNA sequencing (scRNA-seq) and single-cell high-throughput chromosome conformation capture (scHi-C), have deepened our...
22. Apr. 2024 · Results: We developed C2c (“high” or upper case C to “micro” or lower case c), a computational tool based on a residual neural network to learn the mapping between Hi-C and Micro-C contact matrices and then predict Micro-C contact matrices based on Hi-C contact matrices.
6. Mai 2024 · The Hi-C (high-throughput chromatin conformation capture) method has been increasingly used in recent years as an alternative approach for detecting various types of chromosomal rearrangements. The advantage of the method is its ability to detect balanced rearrangements at a lower sequencing depth. This efficiency is partly due to ...
8. Mai 2024 · The HiFi method included in this collection improves sequence accuracy, solving the major problems of long read data and enabling the construction of more accurate genomes. And, most studies in...
10. Mai 2024 · HiC sequencing is a DNA-based next-generation sequencing method that preserves the 3D conformation of the genome, facilitating detection of genomic rearrangements. HiC was 100% concordant with clinical diagnostic testing workflows for detecting clinically significant genomic rearrangements in pediatric leukemia and rhabdomyosarcoma specimens.
