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  1. journals.plos.org › ploscompbiol › articleLearning Micro-C from Hi-C with diffusion models

    17. Mai 2024 · In this subsection, we first explore the effect of different Hi-C sequencing depths as input, and then determine whether random sample (x T in Algorithm 2) affect the robustness of HiC2MicroC. Finally, we try to prove noise level serves a crucial role during prediction.

  2. www.nature.com › articles › s41588/024/01745-3GAGE-seq concurrently profiles multiscale 3D genome ... - Nature

    14. Mai 2024 · Advances in single-cell technologies, such as single-cell RNA sequencing (scRNA-seq) and single-cell high-throughput chromosome conformation capture (scHi-C), have deepened our...

  3. www.nature.com › articles › s41597/024/03437-3Haplotype-resolved chromosome-level genome assembly of Huyou

    Vor 19 Stunden · By combining PacBio and Hi-C sequencing, we generated a primary genome assembly and two haplotypes, comprising nine pseudo-chromosomes, with sizes of 339.91 Mb, 323.51 Mb, and 311.89 Mb ...

  4. pubmed.ncbi.nlm.nih.gov › 38765974Evaluation of Hi-C sequencing for the detection of gene ... -...

    10. Mai 2024 · HiC sequencing is a DNA-based next-generation sequencing method that preserves the 3D conformation of the genome and has shown promise in detecting genomic rearrangements in translational research studies.

  5. link.springer.com › chapter › 10Graph-Based Genome Inference from Hi-C Data | SpringerLink

    17. Mai 2024 · Hi-C, a high-throughput, sequencing-based technique, has drastically expanded our comprehension of 3D chromosome structures. The first step of Hi-C analysis pipelines involves mapping sequencing reads from Hi-C to linear reference genomes.

  6. link.springer.com › article › 10The first high-quality genome assembly and annotation of

    10. Mai 2024 · This study showcases the successful assembly of the UF-T48 lantana breeding line, a complex genome, using a combination of PacBio HiFi long-read sequencing and Hi-C data. This approach facilitated the creation of the first chromosome-scale, haplotype-phased assembly for Lantana camara.

  7. www.medrxiv.org › content › 10Evaluation of Hi-C sequencing for the detection of gene fusions...

    12. Mai 2024 · HiC sequencing is a DNA-based next-generation sequencing method that preserves the 3D conformation of the genome and has shown promise in detecting genomic rearrangements in translational research studies.