Suchergebnisse
Suchergebnisse:
Vor 3 Tagen · The presence of low blood pressure, high blood lactate, or low urine output may suggest poor blood flow. Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement. Sepsis is caused by many organisms including bacteria, viruses and fungi.
Vor 2 Tagen · An increased blood lactate clearance may be explained by enhancing mitocondrial utilization of NADH. Actually, we found that an increased mitochondrial complex I activity was associated with lower mortality in the intensive care unit (ICU). However, neither mechanism fully explains the increase in lactate levels in sepsis.
18. Mai 2024 · This study highlights the significance of lactate level trends over time for the prediction of mortality in the PICU in patients with severe sepsis or septic shock. Elevated lactate levels and decreased lactate clearance six hours after hospitalisation are associated with a higher mortality rate.
16. Mai 2024 · Abstract. Traditionally, lactate has been considered a ‘waste product’ of cellular metabolism. Recent findings have shown that lactate is a substance that plays an indispensable role in various physiological cellular functions and contributes to energy metabolism and signal transduction during immune and inflammatory responses.
Vor 5 Tagen · As lactate is not measured on our cord blood gases, the initial lactate value reflects a postnatal level obtained within the first 4 h of life. Difference in values at 12 and 24 h were calculated ...
Vor 2 Tagen · Lactate uptake by the liver is diminished with metformin use because lactate is a substrate for hepatic gluconeogenesis, a process that metformin inhibits. In healthy individuals, this slight excess is cleared by other mechanisms (including uptake by unimpaired kidneys), and no significant elevation in blood levels of lactate occurs.
The normal blood lactate concentration in an unstressed patient is 0.5-1 mmol/L. Hyperlactemia is defined as a mild to moderate increase in blood lactate concentration (2-4 mmol/L) without...
