Suchergebnisse
Suchergebnisse:
In human cell lines, chaperone proteins were found to compose ~10% of the gross proteome mass, and are ubiquitously and highly expressed across human tissues. Chaperones are found extensively in the endoplasmic reticulum (ER), since protein synthesis often occurs in this area.
Chaperone (engl. Anstandsdamen) sind Proteine, die neu synthetisierte Proteine bei der Faltung unterstützen. Die Bezeichnung wurde nach der englischen Bezeichnung für Anstandsdame gewählt, „da sie unreife Proteine vor schädlichen Kontakten bewahren“.
22. Aug. 2023 · Chaperones are a group of proteins that have functional similarity and assist in protein folding. They are proteins that have the ability to prevent non-specific aggregation...
10. Jan. 2020 · Chaperone sind Proteine, die in Zellen für die korrekte Faltung anderer komplexer Proteine sorgen. Sie kommen bei Prokaryoten und Eukaryoten vor. Funktionsprinzip. In der Aminosäuresequenz der Proteine ist die räumliche Konformation und Art der Faltung prinzipiell festgelegt.
20. Juli 2011 · We define a molecular chaperone as any protein that interacts with, stabilizes or helps another protein to acquire its functionally active conformation, without being present in its final ...
Chaperone proteins, or molecular chaperones, are proteins that assist others to fold properly during or after synthesis, to refold after partial denaturation, and to translocate to the cellular locales at which they reside and function. Chaperones are also involved in the regulation of their own genes and in the presentation of proteins ...
12. Apr. 2021 · For each member, we mined the literature to determine whether it functions as a chaperone that transiently assists the folding, unfolding, assembly or disassembly of proteins and protein...
22. Dez. 2017 · Protein folding factors (chaperones) are required for many diverse cellular functions. In striated muscle, chaperones are required for contractile protein function, as well as the larger scale assembly of the basic unit of muscle, the sarcomere.
2. Feb. 2019 · Molecular chaperones are nature's solution to these challenges. They assist other proteins in acquiring and maintaining their structures, support cellular processes, and even link the activity of proteins to the stress status of the cell.
28. Nov. 2022 · Chaperone proteins have crucial roles to play in all animal species and are involved in mediating both the folding of newly synthesized peptides into their mature conformation, the refolding of misfolded proteins, and the trafficking of proteins between subcellular compartments.
