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  1. 16. Jan. 2018 · He challenged his head chemist, Harold Watkins, to make a sweet, liquid form of sulfanilamide. After much experimentation, Watkins found that a solvent, diethylene glycol, could dissolve...

  2. www.fda.gov › about-fda › histories-product-regulationSulfanilamide Disaster | FDA

    The company's chief chemist and pharmacist, Harold Cole Watkins, experimented and found that sulfanilamide would dissolve in diethylene glycol. The company control lab tested the mixture for...

  3. DEG is poisonous to humans and other mammals, but Harold Watkins, the company's chief pharmacist and chemist, was not aware of this. (Although the first case of a fatality from the related ethylene glycol occurred in 1930 and studies had been published in medical journals stating DEG could cause kidney damage or failure, its toxicity ...

  4. 1. Jan. 2022 · The Massengill chief chemist, Mr. Harold Watkins, used diethylene glycol (DEG), a cheap sweet-tasting solvent, and raspberry extract to formulate a preparation more agreeable, especially for children, who could not or would not take tablets or capsules of the drug ( Federal Register, 1937 ).

    • Alan D. Woolf
    • 2022
  5. 4. Okt. 2019 · The firm’s chemist apparently did not share this feeling; Harold Watkins committed suicide after learning of the effects of his latest concoction. Through the dogged persistence of federal, state, and local health agencies and the effects of the AMA and the news media, most of the elixir was recovered.

    • 5 Min.
  6. BRISTOL, Tenn., Jan. 18. A coroner’s verdict was reserved today in the death of Harold Cole Watkins, chemist who prepared the formula for elixir of sulfanilamide which was blamed for the deaths of 67 persons in 1937. Watkins, 58, was found dead of a bullet wound through the heart at his home. .

  7. 1. Okt. 2022 · But sulfanilamide didn’t taste very good, so the company’s chief chemist, Harold Cole Watkins, added other substances to the solution, including raspberry extract, saccharin, caramel—and the...