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13. Feb. 2018 · This review focuses on the current threats and challenges when dealing with biofilms formed by Candida albicans, Candida glabrata, Candida tropicalis, and Candida parapsilosis, highlighting the differences between the four species. Biofilm characteristics depend on the ability of each species to produce extracellular polymeric ...
- Mafalda Cavalheiro, Miguel Cacho Teixeira
- 10.3389/fmed.2018.00028
- 2018
- Front Med (Lausanne). 2018; 5: 28.
- Transcriptional Pathways to The Development of Candida Biofilms
- Interactions of Candida Albicans in Polymicrobial Biofilms
- Biofilm Treatment
Biofilm formation is a complex and multistep process controlled by a wide array of transcriptional regulators (TRs). TRs are of central importance owing to their influence on microbial response to environmental stimuli and can alter cellular development and routine biological functions of cells through promoter binding of many genes, including othe...
Multiple species having beneficial, synergistic as well as antagonistic interactions can be part of polymicrobial biofilms . It has also been reported that approximately 27–56% of hospital-acquired bloodstream infections of C. albicans are polymicrobial [4, 60]. In fact, they often exist as complex, diverse, and heterogeneous cellular communities o...
As mentioned earlier, Candida spp. biofilms are responsible for recurrent and chronic infections and are additionally tolerant and/or resistant to different antifungal compounds as well as the innate immune system . Different studies conclude that the complex structure of the biofilm determines the antifungal susceptibility of C. albicans [19, 77, ...
- Patrícia Pimentel de Barros, Rodnei Dennis Rossoni, Cheyenne Marçal de Souza, Liliana Scorzoni, Juli...
- 2020
In this review, we focus on Candida albicans biofilms, which can colonize mucosal surfaces, such as those coating the oral and vaginal epithelia, and implanted medical devices, such as prosthetics, heart valves, and catheters, and can seed systemic infections in humans (see Fig 1 for common C. albicans biofilm-associated infections occurring ...
- Megha Gulati, Clarissa J. Nobile
- 10.1016/j.micinf.2016.01.002
- 2016
- 2016/05
23. Aug. 2019 · The opportunistic fungal pathogen Candida albicans is capable of adhering to the oral mucosa despite forces created by salivary flow. Although many fungal adhesion proteins have been identified...
- Andrew D. McCall, Ruvini U. Pathirana, Aditi Prabhakar, Paul J. Cullen, Mira Edgerton
- 2019
22. Sept. 2023 · The formation of Candida biofilms has been observed on multiple surfaces, including living surfaces (mucous membranes, organs, blood vessels) and non-living surfaces, most often in the case of medical devices that come into contact with patients’ bodies (stents, shunts, implants, endotracheal tubes, pacemakers, and multiple types ...
- Zuzana Malinovská, Eva Čonková, Peter Váczi
- J Fungi (Basel). 2023 Oct; 9(10): 955.
- 10.3390/jof9100955
- 2023/10
18. März 2023 · Candida biofilms are important in superficial and deep infections. The mucosal barriers of the oral cavity, oropharynx, respiratory, gastrointestinal, and genitourinary tracts are all potential sites for the genus Candida to reside, colonize and potentially initiate pathogenesis.
9. Okt. 2020 · Biofilm formation by host-associated Candida species of fungi occurs on both tissue surfaces and implanted devices, contributing to host colonization and disease. In C. albicans, biofilms are ...
