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  1. RNA INTERFERENCE. This year’s Nobel Prize in Physiology or Medicine is shared by Professor Andrew Z. Fire at Stanford University, California, USA, and Professor Craig C. Mello at the University of Massachusetts Medical School in Worcester, USA. They receive the prize for their discovery that double-stranded RNA triggers suppression of gene ...

  2. 28. Nov. 2011 · Fire and Mello called the process RNA interference (RNAi), and won the Nobel Prize in Physiology or Medicine in 2006 for their discovery. Fire was born on 27 April 1959 in Stanford, California, to Janet and Philip Fire. The young Fire spent his childhood in Sunnyvale, California, where he graduated from Fremont High School at the age of fifteen.

  3. Andrew Fire's 323 research works with 48,302 citations and 8,575 reads, including: DNA polymerase diversity reveals multiple incursions of Polintons during nematode evolution

  4. We report here the Nobel Lecture delivered by Professor Andrew Z Fire. Together with the accompanying lecture by Professor Mello this lecture describes the exciting years leading to the discovery of RNA interference (RNAi) and some of the underlying molecular mechanisms. Professor Fire nicely points out his own contribution and the contribution ...

  5. The Nobel Laureates in Physiology or Medicine for 2006, the American scientists Andrew Fire and Craig Mello, have discovered a fundamental mechanism of gene regulation. They have shown that double-stranded RNA molecules can silence a gene by elimination of the mRNA corresponding to that gene. This is called RNA interference (RNAi) and occurs in ...

  6. to Andrew Z. Fire and Craig C. Mello for their discovery concerning a mechanism of gene silencing in cells called RNA interference. In the studies published in 1998 they discovered, that some genes can be silenced by degradation of their mRNA. This degradation is activated by double stranded RNA. RNA interference occurs in plants, animals and ...

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