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Vor 5 Tagen · We then also determined the role of YTHDC1 in acute seizures induced by PTZ kindling, and the results revealed that DG-specific over-expression of YTHDC1 could alleviate seizure-like behaviors, as well as decrease the expression of IEGs induced by PTZ administration. According to these findings, we propose that the METTL14-YTHDC1-m6A axis plays a key role during seizure-like behaviors. Future ...
Vor einem Tag · AbstractPurpose:. Liquid biopsy (LBx) for tumor profiling is increasingly used, but concerns remain regarding negative results. A lack of results may truly reflect tumor genomics, or it may be a false negative that would be clarified by tissue testing. A method of distinguishing between these scenarios could help clarify when follow-on tissue testing is valuable.Experimental Design:. Here we ...
Vor 5 Tagen · Advancements in synthetic biology have facilitated the incorporation of heterologous metabolic pathways into various bacterial chassis, leading to the synthesis of targeted bioproducts. However, total output from heterologous production pathways can suffer from low flux, enzyme promiscuity, formation of toxic intermediates, or intermediate loss to competing reactions, which ultimately hinder ...
Vor 5 Tagen · Z. album was collected from Marsa Matrouh at the Northern Coast of the Mediter-ranean Sea in Egypt during May 2019. It was identified at the Faculty of Science, Alexan-dria University. A voucher specimen was kept under registration number ZA-2019 in the herbarium of the Pharmacognosy Department, Faculty of Pharmacy, Suez Canal University,
Vor 3 Tagen · Scientists have found the genetic root of a disorder that causes intellectual disability, which they estimate affects as many as one in 20,000 young people. And they hope their discovery leads to a new diagnosis that can provide answers to families.
Vor 3 Tagen · Alan Parsons hat das im Booklet zur TALES OF MYSTERY.. - BD sehr ausführlich erklärt. - BD sehr ausführlich erklärt. Voraussetzung ist natürlich vorhandenes Originalmaterial.
Vor 4 Tagen · Cradling the darkness together, kindling the light. May 31, 2024 by Victoria Emily Jones. Mary and Elizabeth by Laurie Gudim. Two women, both pregnant, greet each other—and an instantaneous bond is formed between and deep within them, confirming their identities as bearers of life. In this astonishing moment of communion, each is strengthened ...
