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1. www.nature.com › articles › s43587/024/00647-7Epigenetic and proteomic signatures associate with clonal...

   www.nature.com › articles › s43587/024/00647-7

   Vor 4 Tagen · Exploring the clonal expansion of somatically mutated hematopoietic stem cells with aging, Mack, Raddatz et al. quantify rates of clonal expansion in 4,370 individuals in the Trans-Omics for ...

2. onlinelibrary.wiley.com › doi › 10Accelerated Aging after Traumatic Brain Injury ... - Wiley Online...

   onlinelibrary.wiley.com › doi › 10

   Vor einem Tag · One explanation for this upward inflection in sample education is age-related attrition in less educated individuals (e.g., due to mortality and dementia 50) and greater health and resilience factors associated with advanced education, which is a modifier of MRI brain volume. 51 Aging with TBI is distinct from TBI during aging, partly because TBIs sustained in older individuals are more likely ...

3. www.nature.com › nataging › research-articlesResearch articles | Nature Aging

   www.nature.com › nataging › research-articles

   Vor 4 Tagen · Aging atlas reveals cell-type-specific effects of pro-longevity strategies. This comprehensive resource offers new insights into how different types of cell and tissue change with age in C....

4. www.biorxiv.org › content › 10Human Brain Aging is Associated with Dysregulation of Cell-Type...

   www.biorxiv.org › content › 10

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   Vor 5 Tagen · Significant links between aging and DNA methylation are emerging from recent studies. On the one hand, DNA methylation undergoes changes with age, a process termed as epigenetic drift. On the other hand, DNA methylation serves as a readily accessible and accurate biomarker for aging.

5. newatlas.com › medical › rare-disease-genetic-mechanism-agingGenetics of aging uncovered with rare disease discovery - New...

   newatlas.com › medical › rare-disease-genetic-mechanism-aging

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   Vor 3 Tagen · Retinal vasculopathy with cerebral leukoencephalopathy (RVCL) is an SVD caused by an inherited mutation in the TREX1 gene. It’s rare, with fewer than 200 known cases worldwide. Symptoms develop ...

6. link.springer.com › chapter › 10Repurposing of Drugs in Aging | SpringerLink

   link.springer.com › chapter › 10

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   Vor 2 Tagen · The repurposing of drugs has a number of potential benefits in the context of becoming older. To begin, it enables researchers to avoid the time-consuming and financially burdensome process of creating new therapies from the ground up, which may take anywhere from 10 to 15 years and cost billions of dollars.

7. www.nature.com › nataging › articlesArticles | Nature Aging

   www.nature.com › nataging › articles

   Vor 4 Tagen · Through spatial and single nuclear profiling, the authors identify a selective type 2 myofiber pathology in IBM, linked to genomic stress and denervation.