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  1. Vor 18 Stunden · You hold on to the roundabout, try to stay with your friends, trying to stay forever in emergence, in transformation, without actually transforming into anything particular, or emerging as anything specific. One by one, the roads to exit the roundabout close off. The imaginal cells wither. The catalyzing archetypes fade. The lifetime of latent ...

  2. Vor einem Tag · A distinct cell cycle redeploys many canonical cell cycle regulators to control the differentiation of multiciliated cells, with the transcription factor E2F7 playing a pivotal part in this ...

  3. Vor 2 Tagen · Despite significant progress in understanding epigenetic reprogramming of cells, the mechanistic basis of “organ reprogramming” by (epi-)gene–environment interactions remained largely obscure. Here, we use the ether-induced haltere-to-wing transformations in Drosophila as a model for epigenetic “reprogramming” at the whole organism level.

  4. Vor einem Tag · Teresa eventually began to write about her spiritual experiences, which included hearing voices and experiencing visions during ecstatic states of rapture in which she felt herself being lifted from the ground by a powerful force outside of her control. QUESTIONED FOR HERESY The cell was cold. There was no table or chair. Only a rough, straw ...

  5. Vor 3 Tagen · After washing, cells were resuspended in 750 µl of D-PBS/BSA and mixed with anti-Biotin-MACSiBeads (Miltenyi Biotec) for 15 min. Unwanted cells labeled by the biotinylated antibody-MACSiBead ...

  6. Vor 5 Tagen · Increasing evidence of brain-immune crosstalk raises expectations for the efficacy of novel immunotherapies in Alzheimer’s disease (AD), but the lack of methods to examine brain tissues makes it difficult to evaluate therapeutics. Here, we investigated the changes in spatial transcriptomic signatures and brain cell types using the 10x Genomics Visium platform in immune-modulated AD models ...

  7. Vor 2 Tagen · Simultaneous measurements of cell area and cell color in individual cells responding to NE showed that iridophore cell area increases on average by ~25%, and that this change precedes a gradual change in color (SI Appendix, Fig. S6). Importantly, cells treated with nocodazole prior to NE treatment still show this ~25% increase in size, but they do not change color. This result argues that the ...