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Sir Peter John Ratcliffe FRS (* 14. Mai 1954 in Morecambe, Lancashire) ist ein britischer Nephrologe und Professor an der University of Oxford. Er ist einer von drei Trägern des Nobelpreises für Physiologie oder Medizin 2019, für seine Forschungen zum Sauerstoff in Zellen.
Ratcliffe is best known for his work on cellular reactions to hypoxia, for which he shared the 2019 Nobel Prize in Physiology or Medicine with William Kaelin Jr. and Gregg L. Semenza.
Sir Peter J. Ratcliffe. The Nobel Prize in Physiology or Medicine 2019. Born: 14 May 1954, Lancashire, United Kingdom. Affiliation at the time of the award: University of Oxford, Oxford, United Kingdom; Francis Crick Institute, London, United Kingdom.
Sir Peter Ratcliffe. FRS. Professor of Clinical Medicine. My laboratory works on understanding the mechanisms by which cells sense and signal hypoxia (low oxygen levels). Oxygen is of fundamental importance for most living organisms, and the maintenance of oxygen homeostasis is a central physiological challenge for all large animals.
7. Okt. 2019 · William G. Kaelin Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza discovered how cells can sense and adapt to changing oxygen availability. They identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.
10. Mai 2024 · Peter J. Ratcliffe, British scientist known for his research on erythropoietin, a hormone that influences red blood cell production, and for his research on oxygen-sensing mechanisms in cells. His insights into how cells sense oxygen earned him a share of the 2019 Nobel Prize for Physiology or Medicine.
7. Okt. 2019 · Sir Peter Ratcliffe, a clinician scientist at Oxford University and Francis Crick Institute, discovered how cells sense and respond to low oxygen levels. He and his colleagues revealed the mechanism of hypoxia and its role in diseases such as anaemia and cancer.
