Yahoo Suche Web Suche

Suchergebnisse

  1. Suchergebnisse:
  1. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and ...

  2. 21. März 2024 · Definition. Als Acetylcholinesterasehemmer bezeichnet man Substanzen, die im synaptischen Spalt die Wirkung des Enzyms Acetylcholinesterase (AChE) hemmen. Wirkmechanismus. Cholinerge Neurone übertragen ihre Erregung durch Ausschüttung von Acetylcholin in den synaptischen Spalt. Dort bindet es an die sekundärseitigen Rezeptoren.

  3. Cholinesterase inhibitors are medicines that block the breakdown of acetylcholine, a neurotransmitter involved in memory and learning. They are used to treat dementia in Alzheimer's disease, but may cause side effects such as nausea and confusion.

  4. The enzyme Acetylcholin esterase, and its inhibition, plays a role in the development of myofascial trigger points and the associated myofascial pain syndrome. By injecting a mouse with acetylcholin esterase inhibitors and electrical stimulation, the muscle develops trigger points .

  5. Hence, acetylcholinesterase inhibitors, interacting with the enzyme as their primary target, are applied as relevant drugs and toxins. This review presents an overview of toxicology and pharmacology of reversible and irreversible acetylcholinesterase inactivating compounds.