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  1. General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the ...

  2. 1. Juni 2018 · General paresis (or paralysis) of the insane (GPI) was crippling and terminal. It ended in loss of control over mind and body, often accompanied by grandiose delusions of wealth and power and, finally, paralytic death. There was no known cause. Could GPI be caused by overwork? Emotional labour? Mental strain? Sexual promiscuity ...

    • Kelley Swain
    • 2018
  3. 3. Okt. 2012 · Learn about the history of general paralysis of the insane (GPI), a fatal disease that affected men in the 19th century. Find out how GPI was linked to syphilis, alcohol, and degeneration, and how it was diagnosed and treated in asylums.

  4. General paresis of insane is a parenchymal brain disease where antibiotics can only stop progression of the disease but cannot bring complete cure. A high index of suspicion as needed to diagnose the cases of neurosyphilis which generally lack the typical neurological and ophthalmological findings. This case underlines the need to consider the ...

    • Suravi Patra, Ajaya Mishra
    • 2010
  5. General paresis of insane is a progressive disease of the brain leading to mental and physical worsening. It is important to consider tertiary syphilis in the differential diagnosis of dementia.

    • Shri Ram Sharma, Masaraf Hussain, Debojit Roy
    • 2020
  6. 8. Juli 2010 · Parenchymatous syphilis manifests as two processes: paretic neurosyphilis (a.k.a. “general paralysis of the insane,” general paresis, or “dementia paralytica”) and tabetic neurosyphilis (a.k.a. “tabes dorsalis” or “progressive locomotor ataxy”).

  7. 13. Jan. 2021 · General paresis of the insane (GPI), also termed dementia paralytica, is one of the most common late forms of neurosyphilis, accounting for about 38.9–49.0% of total neurosyphilis reported by other investigations Citation 3, Citation 4 and 40.0% by our previous study.