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  1. 20. Juli 2021 · Candida glabrata is an opportunistic pathogen that adheres to human epithelial mucosa and forms biofilm to cause persistent infections. In this work, Single-cell Force Spectroscopy (SCFS) was...

  2. 17. Aug. 2021 · Recent evidence indicates that most IC caused by C. glabrata is associated with biofilm growth . Candida glabrata biofilms show antifungal resistance characterised by a compact, dense structure of yeast cells.

    • Yahaya Hassan, Yahaya Hassan, Shu Yih Chew, Leslie Thian Lung Than
    • 10.3390/jof7080667
    • 2021
    • J Fungi (Basel). 2021 Aug; 7(8): 667.
  3. 1. März 2017 · Candida glabrata biofilms are extremely refractory to antimicrobial therapy and more difficult to manage due to the natural properties mode of growth. They are able to withstand much higher concentrations of antifungal drugs compared with the planktonic cells, making C. glabrata biofilm infections extremely challenging to treat.

    • Célia Fortuna Rodrigues, Maria Elisa Costa Rodrigues, Sónia Carina Silva, Mariana Henriques
    • 10.3390/jof3010011
    • 2017
    • J Fungi (Basel). 2017 Mar; 3(1): 11.
  4. 16. Dez. 2015 · Candida glabrata is one of the pathogenic yeasts that is responsible for life-threatening disseminated infections and able to form biofilms on medical devices such as vascular and urinary catheters.

    • Christophe d'Enfert, Christophe d'Enfert, Guilhem Janbon, Guilhem Janbon
    • 2016
  5. 22. Sept. 2023 · In human medicine, there is an increasing proportion of immunocompromised patients with prolonged hospitalization, and patients with long-term inserted drains, cannulas, catheters, tubes, or other artificial devices, that exhibit a predisposition for colonization by biofilm-forming yeasts.

  6. 1. März 2011 · In addition to the high antifungal drugs resistance and inability to form hyphae or secret hydrolases, C. glabrata retain many virulence factors that contribute to its extreme aggressiveness and result in a low therapeutic response and serious recurrent candidiasis, particularly biofilm formation ability.