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  1. 1. März 2024 · Being overweight or obese can have a serious impact on health. Carrying extra fat leads to serious health consequences such as cardiovascular disease (mainly heart disease and stroke), type 2 diabetes, musculoskeletal disorders like osteoarthritis, and some cancers (endometrial, breast and colon).

  2. 11. Sept. 2023 · This Review summarizes the current understanding of a number of potential physiological mechanisms underlying weight regain after weight loss, including: the role of adipose tissue immune...

  3. 17. Jan. 2019 · Weight regain after weight loss has large interindividual variation. Although many factors probably contribute to this variation, we hypothesize that variability in biological responses...

    • Marleen A van Baak, Edwin C M Mariman
    • 2019
  4. 19. Nov. 2014 · Abstract. Obesity is associated with multiple negative health consequences and current weight management guidelines recommend all obese persons to lose weight. However, recent evidence suggests that not all obese persons are negatively affected by their weight and that weight loss does not necessarily always improve health.

    • R. E. Brown, J. L. Kuk
    • 2015
  5. 23. Aug. 2023 · Data suggest that weight loss and weight loss maintenance are physiologically and psychologically different in many ways. Consequently, individuals may require different interventions designed...

  6. 30. Dez. 2017 · Many people with normal weight want to lose weight, and they repeat losing and gaining weight multiple times through their lives. This is called “weight cycling.”. Recent studies report not just the negative impact of being obese, but also the danger of weight cycling for cardiometabolic health.

  7. Biological regulation is first discussed in relation to other nonbiological pressures that affect body weight as weight is gained, lost, and regained. The specific biological adaptations to the most common form of dieting, an energy-restricted low-fat diet, are then discussed in more detail.