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  1. lincsproject.orgNIH LINCS Program

    Systematic assessment of the molecular and cellular phenotypes induced by these ligands comprise the LINCS Microenvironment (ME) perturbation dataset, which has been curated and made publicly available for community-wide analysis and the development of novel hypotheses and computational methods.

    • Home

      To develop a detailed understanding of the linkage between...

    • About

      This will constitute the largest such public dataset,...

    • Centers

      The LINCS program is currently in phase II after the...

    • Data

      Once collected, LINCS data is made available to the research...

    • Tools

      LINCS Tools Marketplace. Tools and tutorials to help you be...

    • Community

      The NIH LINCS Program and the Connectivity Map at the Broad...

    • Publications

      LINCS Publications. Discover and cite publications from the...

    • News

      See HMS LINCS Dataset #20258 for a comparison of metrics...

  2. lincsproject.org › LINCS › dataNIH LINCS Program

    Once collected, LINCS data is made available to the research community in various formats so that it can be used in different types of analyses. The data standards page describes the data structures that are being developed by the LINCS Data Working Group.

  3. lincsproject.org › LINCS › toolsNIH LINCS Program

    Find the best place to obtain the LINCS L1000 data; Download RNA-Seq data from LINCS; Find attributes about genes and proteins for machine learning; Search LINCS metadata through APIs; Find proteomic and epigenomic data from the same conditions profiled by the L1000 assay

  4. lincs.hms.harvard.edu › dbHMS LINCS Database - HMS LINCS Project - Harvard University

    The Database contains all publicly available HMS LINCS datasets and information for each dataset about experimental reagents (small molecule perturbagens, cells, antibodies, and proteins) and experimental and data analysis protocols.

  5. lincs.hms.harvard.edu › dataData - HMS LINCS Project

    All HMS LINCS data are available by browsing or searching the HMS LINCS Database, and many datasets can be visualized through customized graphical browsers accessible through our publication and project summary pages.

  6. commonfund.nih.gov › LINCSLibrary of Integrated Network-based Cellular Signatures (LINCS)

    The Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program is developing a library of molecular signatures that describes how different types of cells respond to a variety of agents that disrupt normal cellular functions, called “perturbagens.”

  7. currentprotocols.onlinelibrary.wiley.com › doi › fullGetting Started with LINCS Datasets and Tools - Xie - 2022 -...

    25. Juli 2022 · Basic Protocol 1: Navigating L1000 tools and data in CLUE.io. Basic Protocol 2: Computing signatures from the L1000 data with the CD method. Basic Protocol 3: Analyzing lists of differentially expressed genes and querying them against the L1000 data with BioJupies and the Bulk RNA-seq Appyter.