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Vor einem Tag · X-ray crystallography is a robust and widely used technique that facilitates the three-dimensional structure determination of proteins at an atomic scale. This methodology entails the growth of protein crystals under controlled conditions followed by their exposure to X-ray beams and the subsequent analysis of the resulting diffraction patterns via computational tools to determine the three ...
Vor 5 Tagen · Methods commonly used to study protein structure and function include immunohistochemistry, site-directed mutagenesis, X-ray crystallography, nuclear magnetic resonance and mass spectrometry. History and etymology
Vor 4 Tagen · X-ray topography is an imaging technique based on Bragg diffraction. Diffraction topographic images record the intensity profile of a beam of X-rays diffracted by a crystal. A topography thus represents a two-dimensional spatial intensity mapping of reflected X-rays, i.e. the spatial fine structure of a Laue reflection.
Vor 2 Tagen · Compared to x-ray crystallography, TEM analysis is significantly more localized and can be used to obtain information from tens of thousands of atoms to just a few or even single atoms. Formation of a diffraction pattern
Vor 3 Tagen · In the bpRNA database, Danaee et al. also collected some PDB-derived RNA secondary structures that were parsed only from the 3D structures obtained using X-ray crystallography and NMR techniques. We downloaded these PDB-derived results and prepared a source-independent test set named TestSetγ. As in TestSetβ, only sequences represented using AU(T)GC were retained. In addition, to have a fair ...
Vor 2 Tagen · Marie won the 1911 Nobel Prize in Chemistry for her discovery of the elements polonium and radium, using techniques she invented for isolating radioactive isotopes. Under her direction, the world's first studies were conducted into the treatment of neoplasms by the use of radioactive isotopes.
Vor 4 Tagen · X-rays are used to investigate the structural properties of solids, liquids or gels. Photons interact with electrons, and provide information about the fluctuations of electronic densities in the matter. A typical experimental set-up is shown on Figure 1 : a monochromatic beam of incident wave vector ki is selected and falls on the sample. The scattered intensity is collected as a function of ...
