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  1. 17. Apr. 2024 · DAVID is a database and a set of tools for analyzing gene lists and finding biological themes, pathways, and interactions. It is used by researchers from over 100 countries and has over 69K citations.

    • Tutorial

      The Functional Annotation Summary provides annotation type...

    • FAQ

      FAQ - DAVID Functional Annotation Bioinformatics Microarray...

    • LHRI Publications

      LHRI Publications - DAVID Functional Annotation...

    • LHRI Presentations

      LHRI Presentations - DAVID Functional Annotation...

  2. 20. Jan. 2021 · Fisher's Exact p -values are computed by summing probabilities p over defined sets of tables (Prob=∑ Ap ). For 2 x 2 tables, one-sided p -values for Fisher's Exact test are defined in terms of the frequency of the cell in the first rows and first column of the table, the (1,1) cell. Denote the observed (1,1) cell frequency by n11, for a right ...

    • New David Gene System
    • Knowledgebase Update
    • New Annotation Types Added to Knowledgebase
    • Updated Display of ‘Annotation Summary Results’
    • Updated Gene Symbol Upload Process
    • Expansion of Gene Report
    • Documentation Update and User Support

    Between 2007 and 2016, the DAVID Knowledgebase had a centralized gene identifier (DAVID Gene ID) to agglomerate redundant gene/protein IDs and associated heterogeneous annotation contents from different annotation databases (13,14). With improved cross-referencing between NCBI, EMBL-EBI and DDBJ, NCBI’s Entrez Gene ID had similar coverage for annot...

    Based on the new DAVID Gene System, all existing annotation types in the DAVID Knowledgebase have been updated, if available. Compared with DAVID v6.8, the numbers of gene-term records have increased for 73 out of 78 existing annotation types that have been updated with 58 of them doubling at the minimum (Figure 2C, Supplemental Data 1). The remain...

    We continue to seek annotation from new databases to enrich DAVID. For this update, the new annotations include small molecule-gene interactions from PubChem (20), drug-gene interactions from DrugBank (21), gene–disease associations from DisGeNET (22), pathways from WikiPathways (23) and PathBank (24), and tissue expression data from the Human Prot...

    Upon starting functional analysis of a gene list in DAVID, the Annotation Summary Results page will display up to ten annotation categories in DAVID v6.8, depending on available annotations associated with the genes in the list. Besides the additional annotation types added to the categories described above, we have renamed or removed some annotati...

    Of the 1 047 937 gene/protein lists uploaded to DAVID 6.8 in 2021, the top uploaded gene identifier type was gene symbol (Supplementary Figure S2). Due to the ambiguous nature of gene symbols whereby one symbol may map to multiple species, a gene symbol list uploaded to DAVID would result in the list being mapped to all relevant species and exponen...

    The DAVID Gene Report contains the annotations specific to a given gene available in the DAVID Knowledgebase and is accessible from all DAVID tools. A detailed description can be found in the Supplemental Information. In this update, when available, the following new annotations associated with the DAVID Gene have been added to the gene report: Uni...

    To better serve the community, we have updated the documentation of DAVID including all technical documents and the FAQ. We have also improved the navigation of the DAVID webpages with optimized pull-down menus to make access more efficient. The latest improvements and news concerning DAVID are now included on the home page. Users are actively supp...

  3. 14. Aug. 2003 · DAVID, a web-accessible program that integrates functional genomic annotations with intuitive graphical summaries, has been described and will assist in the interpretation of genome-scale datasets by facilitating the transition from data collection to biological meaning.

    • Glynn Dennis, Brad T. Sherman, Douglas A Hosack, Jun Jun Yang, Wei Gao, H. Clifford Lane, Richard A....
    • Genome Biol. 2003; 4(9): R60.
    • 2003
    • 2003
  4. README. For given genes, to access the corresponding heterogeneous functional annotations, which cover over 50 categories from dozens of public databases , in a high-throughput manner. For given gene identifiers, to translate to other types of gene identifiers representing the same gene entries in a high-throughput manner.

  5. 5. Juli 2022 · Abstract. DAVID is a popular bioinformatics resource system including a web server and web service for functional annotation and enrichment analyses of gene lists. It consists of a comprehensive knowledgebase and a set of functional analysis tools. Here, we report all updates made in 2021.