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  1. In the industry, organic chemists work in discovery chemistry (making new molecules) and process optimization (finding better synthetic methods for large scale production). The Organic Chemistry Portal offers an overview of recent topics, interesting reactions and information on important chemicals for organic chemists.

  2. Important Organic Reactions. Important transformations that every synthetic chemist should know are, on the one hand, named reactions in order to be able to discuss them with colleagues, but also frequently used C-C and C-N coupling reactions, since they occur quite often in synthesis plans. Of course, all these Pd-catalyzed cross-coupling ...

  3. A totally different approach is diversity-oriented synthesis. In DOS, organic chemists try to use versatile functional groups and let them react with a broad range of substrates, so the products cover a broad chemical space. That include new functionalities with totally different binding properties, ring sizes and 3D configurations.

  4. In laboratory discussions, people very often use name reactions to refer to experiments they are running or the chemical problems they are investigating. The name reaction is a type of shorthand that avoids the need to give a lengthier explanation of the features of a particular transformation of interest. Mentioning the name reaction allows a ...

  5. A protective group (also referred to as "protecting group") is a reversably formed derivative of an existing functional group in a molecule. The protective group is temporarily attached to decrease reactivity so that the protected functional group does not react under synthetic conditions to which the molecule is subjected in one or more ...

  6. Total Synthesis - An Introduction. As a scientific discipline, total synthesis has its formative roots in the mid-19th century, primarily as means for confirmation of structure. In those early days, the analytical tools available to the synthetic chemist were extraordinarily basic, so following in nature's footsteps was essential in the process ...

  7. Oxidizing Agents - A Short Introduction. An oxidizing agent, also known as an oxidant, is a substance that is capable of causing oxidation, a chemical reaction in which electrons are lost. In other words, it is a substance that can accept electrons from another substance, which causes the other substance to lose electrons and become oxidized.