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  1. www.organic-chemistry.org › protectivegroupsProtective Groups - Organic Chemistry Portal

    Learn how to protect and deprotect functional groups in organic molecules with reversible derivatives called protective groups. Find out the stability data, functional groups, and examples of protecting groups for various reactions and applications.

    • Amino

      T. W. Green, P. G. M. Wuts, Protective Groups in Organic...

    • Tert -Butyl Ethers

      Protection. An eco-compatible method for the formation of...

    • Carboxyl

      T. W. Green, P. G. M. Wuts, Protective Groups in Organic...

    • Allyl Ether

      Conversion of Allyl Ethers. Claisen Rearrangement...

  2. chem.libretexts.org › Bookshelves › Organic_Chemistry13.10: Protecting Groups in Organic Synthesis - Chemistry...

    Hydroxyl (OH) ( OH) protecting groups in Organic Synthesis. Protection of alcohols: Acetyl (Ac) ( Ac) – Removed by acid or base. Benzoyl (Bz) ( Bz) – Removed by acid or base, more stable than Ac Ac group. Benzyl ( Bn Bn, Bnl Bnl) – Removed by hydrogenolysis. Bn Bn group is widely used in sugar and nucleoside chemistry.

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  4. en.wikipedia.org › wiki › Protecting_groupProtecting group - Wikipedia

    A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent chemical reaction. It plays an important role in multistep organic synthesis.

  5. ethz.ch › content › damProtecting Groups - Synthesis I (Lecture 8) 1 Introduction - ETH...

    This concept can be extended to any number of functional groups. Amines can be protected by Boc-, Fmoc-, Cbz-, or Alloc protecting groups, which are removed by acids, bases, hydrogenolysis, or the use of transition metals respectively. Each group remains intact under the other reaction conditions.

  6. chemistrytalk.org › protecting-groupsProtecting Groups in Organic Synthesis | ChemTalk

    Protecting Group Basics. Protecting groups add to the existing functional groups to prevent them from future reaction. There are many different protecting groups based on the functional group which needs protection, and the reactions it needs protection from. However, all of these different protecting groups share some qualities.

  7. onlinelibrary.wiley.com › doi › bookGreene's Protective Groups in Organic Synthesis

    10. Apr. 2006 · The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including... …

  8. chem.libretexts.org › Bookshelves › Organic_Chemistry18.12: Protecting Groups - Chemistry LibreTexts

    18.12: Protecting Groups. Page ID. Compound 1.4.1.4A illustrates several important points in Protection / Deprotection protocol. Both the functional groups could react with a Grignard Reagent. Carboxylic acid group would first react with one mole of the Grignard Reagent to give a carboxylate anion salt.